منابع مشابه
Mechanical properties of sickle cell membranes.
The mechanical properties of sickle erythrocyte membranes were evaluated in the ektacytometer. When ghosts from the total red blood cell population were examined, the rigidity of the resealed ghosts and their rate of fragmentation by shear stress (t1/2) were normal. However, fractionation on Stractan density gradients revealed that sickle cells were heterogenous in their membrane mechanical pro...
متن کاملEpiretinal membranes in sickle cell disease.
Epiretinal membranes at the macula were seen in 4% of the eyes of 355 patients with homozygous sickle cell (SS) disease and sickle cell haemoglobin-C (SC) disease under the age of 60 years. The presence of proliferative sickle retinopathy (PSR), the extent of involvement of PSR, and vitreous haemorrhage all constitute risk factors for the formation of epiretinal membranes. The occlusion of PSR ...
متن کاملOxidative stress in sickle cell disease
In the 18th century, Priestley, Scheele and Lavoisier discovered oxygen and reported its critical role and toxic effects in living organisms. In the last century, several studies highlighted the importance of biological oxidation for energy production by aerobic organisms, in defense and the elimination of drugs. Oxidation is mediated by oxidants and free radicals, generically called reactive o...
متن کاملOxidative status in sickle cell anemia
177 xxx They analyzed 651 patients with APL of whom 72 expressed CD56 (11%). CD56 + APL was significantly associated with high white blood cell counts, low albumin levels, the BCR3 isoform and coexpression of the CD2, CD34, CD7, HLA-DR, CD15 and CD117 antigens. For CD56 + APL, the 5-year relapse rate was 22% compared with a 10% relapse rate for CD56-APL (p-value = 0.006). CD56 + APL also showed...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1986
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj2370265